Profile of Developmental Behavioral Pediatrics

Corresponding author: Parvaneh Karimzadeh MD –Shaheed Beheshti University

ABSTRACT:

Background & aims: Developmental delay is one of the most common problems of children referred to Pediatric Neurology Clinics, highlighting the vitality of improving their developmental conditions. While there is literature available on rehabilitation and is effects, there are limited studies regarding treatment treatment of such children using drugs. Since many children with developmental delay have abnormal EEGs, in this study we decideed to treat a group of these children with Na-Valproate, while they were being rehabilitated and evaluate the were being rehabilitated and evaluate the evaluate the effectiveness of this treatment on their developmental behavioral conditions. Material and Methods: Our subjects included patients referred for developmental delay, to the Mofid Children s Hospital, TORCH, they had abnormal EEGs (without seizure). Following clinical, and neuroimaging evaluation the patients were divided into two groups, those receiving treatment with Na-Valproate and Rehabilitation i.e. the experimental group (25 patients), and those having only rehabilitation or the control group (25 patients) These patients were followed and assessed at 6,12 months and 18 months. The data obtained were analyzed using SPSS statistical software.

Results: significant differences were seen in speech, and in mental and behavioral development in both proups. All patients in the experimental group had normal EEGs after 18 months of treatment . While differences in the scores of DQ (developmental quotient) in both group , before and after treatment was significant, remarkable progress was seen in the experimental group when DQ scores between the groups were compared .Conclusion: Na-Valproate used for this group of patients, along with rehabilitation after 18 months of treatment, was found to be very effective in the improvement of their speech, mental and behavioral development .

Keywords: Developmental- Na-Valproate – Rehabilitation